|
Risk
assessors can face tough situations.
Limited
data, limited funding, contradictory guidance...
The Alliance
helps align financial and technical resources
to ensure public
health is protected.
 |
|
Risk Information Exchange
2009 Annual Report
Join our Mailing
List
|
 |
|
Featured Project:
Dose Response Approaches for Nuclear
Receptor-Mediated Modes of Action
This
workshop will study the biology and dose-response
relationships of receptor-driven gene changes, leading
to the key events, which define a mode of action (MOA)
relevant to an adverse human health outcome. The
workshop aims to relate gene changes to phenotypical
endpoints for the key events in the MOA from either a
dose-response and/or a mechanisms perspective, and to
determine the appropriate dose response assessment
techniques based on both an understanding of the MOA and
the response of nuclear receptors. The workshop
will be highly interactive, with participation by
plenary speakers, case-study panel members, and invited
experts in the various disciplines of nuclear receptor
biology, toxicology, and risk assessment from industry,
academia, and government.
Learn More.
|
|
|
|
|
|
|
|
Featured Project:
Beyond Science and Decisions: From Issue Identification to Dose-Response
Assessment
A
multi-party
collaboration to continue
the discussion set forth by the National Academy of
Science’s Science and Decisions: Advancement of Risk
Assessment (2008), toward a unified approach to dose
response assessment. To be conducted under the aegis of
the Alliance for Risk Assessment (ARA), a series of
three meetings is envisioned over the course of a year,
with the ultimate goal of consensus among the
participants on a guidance document highlighting key
considerations for applying dose-response techniques for
common risk assessment applications. The workshops will
be lead by an Expert Panel, and will focus on biological
and statistical issues that relate to dose response
assessment.
Register
to Attend
Learn
More. |
|
|
|
|
|
|
Featured Project: Mercury
Exposure from Broken Light Bulbs
The New Zealand Ministry of
Health asked the Alliance for Risk Assessment to evaluate risk of
mercury exposure from broken compact fluorescent light bulbs (CFLs). This screening level
assessment included discussion on the type(s) of mercury in compact
fluorescent light bulbs and all available information on the variation
of mercury levels in CFL among manufacturers. A review of the latest
dose response assessment values (e.g., RfC, for the type of mercury in
CFLs) will be done.
After this analysis a calculation of risk to
children and adults, based on typical exposure parameters and
assumptions and use of standard risk characterization techniques such as
Hazard Index, was completed.
Read Report
|
|
|
